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A disruption of the circadian cycle__he metabolic and glandular rhythms that are central to our workaday life__eems to be involved in many, if not most, cases of depression; this is why brutal insomnia so often occurs and is most likely why each day__ pattern of distress exhibits fairly predictable alternating periods of intensity and relief.
William Styron Darkness Visible: A Memoir of Madness
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A disruption of the circadian cycle__he metabolic and glandular rhythms that are central to our workaday life__eems to be involved in many, if not most, cases of depression; this is why brutal insomnia so often occurs and is most likely why each day__ pattern of distress exhibits fairly predictable alternating periods of intensity and relief.

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