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The Hedonistic Imperative outlines how genetic engineering and nanotechnology will abolish suffering in all sentient life. This project is ambitious but technically feasible. It is also instrumentally rational and ethically mandatory. The metabolic pathways of pain and malaise evolved only because they once served the fitness of our genes. They will be replaced by a different sort of neural architecture. States of sublime well-being are destined to become the genetically pre-programmed norm of mental health. The world's last aversive experience will be a precisely dateable event.

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Dr. Blockhead's mocking face was solemn for once. 'Modern science is wiping out deviant strains of the human form,' he said. 'In the twenty-first century, genetic engineering will do more than merely eliminate Siamese twins and alligator-skinned people. It will make it hard to find a person with even a slight overbite or a large nose. I can see that future and it makes me shudder. The future looks like- him'Dr. Blockhead pointed at Mulder.'Imagine going through your whole life looking like that,' said Dr. Blockhead.Mulder shrugged. 'It's a tough job- but someone has to do it.