Stephen Fry

The uncomfortable, as well as the miraculous, fact about the human mind is how it varies from individual to individual. The process of treatment can therefore be long and complicated. Finding the right balance of drugs, whether lithium salts, anti-psychotics, SSRIs or other kinds of treatment can be a very hit or miss heuristic process requiring great patience and classy, caring doctoring. Some patients would rather reject the chemical path and look for ways of using diet, exercise and talk-therapy. For some the condition is so bad that ECT is indicated. One of my best friends regularly goes to a clinic for doses of electroconvulsive therapy, a treatment looked on by many as a kind of horrific torture that isn__ even understood by those who administer it. This friend of mine is just about one of the most intelligent people I have ever met and she says, __ know. It ought to be wrong. But it works. It makes me feel better. I sometimes forget my own name, but it makes me happier. It__ the only thing that works._ For her. Lord knows, I__ not a doctor, and I don__ understand the brain or the mind anything like enough to presume to judge or know better than any other semi-informed individual, but if it works for her_. well then, it works for her. Which is not to say that it will work for you, for me or for others.

He knew he could never jingle change in his pocket or park his car like a confident adult, he was the Adrian he had always been, casting a guilty look over a furtive shoulder, living in eternal dread of a grown-up striding forward to clip his ear.But there again, when he sipped at the whiskey his eyes failed to water and his throat forgot to burn. The body shamelessly welcomed what once it would have rejected. At breakfast he demanded not Ricicles and chocolate spread, but coffee and unbuttered toast. And if the coffee was sugared he leapt from it like a colt from an electric fence. He ate the crust and left the filling, guzzled the olives and spurned the cherries. Yet inside he remained the same Adrian who fought down the urge to stand and shout 'Bullocks' during church services, smelt his own farts and wasted hours skimming through National Geographic on the off-chance of seeing a few naked bodies.

If you know someone who__ depressed, please resolve never to ask them why. Depression isn__ a straightforward response to a bad situation; depression just is, like the weather.Try to understand the blackness, lethargy, hopelessness, and loneliness they__e going through. Be there for them when they come through the other side. It__ hard to be a friend to someone who__ depressed, but it is one of the kindest, noblest, and best things you will ever do.

Choking with dry tears and raging, raging, raging at the absolute indifference of nature and the world to the death of love, the death of hope and the death of beauty, I remember sitting on the end of my bed, collecting these pills and capsules together and wondering why, why when I felt I had so much to offer, so much love, such outpourings of love and energy to spend on the world, I was incapable of being offered love, giving it or summoning the energy with which I knew I could transform myself and everything around me.

They had been there. I had seen my mother__ anxious face, desperate to catch my eye and give me a warm smile. I had tried to smile back, but I had not known how. That old curse again. How to smile. If I smiled too broadly it might look like triumphalism; if I smiled too weakly it might look like a feeble bid for sympathy. If I smiled somewhere in between it would, I knew, look, as always, like plain smugness. Somehow I managed to bare my teeth in a manner that expressed, I hope, sorrow, gratitude, determination, shame, remorse and resolve.

He was one of a long line of mimsy and embittered middle-class sensitives who disguised their feeble and decadent lust as something spiritual and Socratic. And why not? If it meant he had to end his days on some Mediterranean island writing lyric prose for Faber and Faber and literary criticism for the New Statesman, running through successions of houseboys and 'secretaries', getting sloshed on Fernet Branca and having to pay off the Chief of Police every six months, then so be it. Better than driving to the office in the rain.

He's your enemy, Donald!''He most certainly is not,' said Trefusis. 'Not unless I say so. He may dearly want to be my enemy, he may beg on bended knee for open hostility of the most violent kind, but it takes two to tangle. I choose my own enemies.

Having a great intellect is no path to being happy.

Those who rule the world get so little opportunity to run about and laugh and play in it.

You can't just say there is a god because the world is beautiful. You have to account for bone cancer in children.

Read it wisely, Little One, for the power of ignorance is great.

If you spend your life on a moral hill-top, you see nothing but the mud below. If, like me, you live in the mud itself, you get a damned good view of clear blue sky and clean green hills above. There's none so evil-minded as those with a moral mission, and none so pure in heart as the depraved.

But you can't argue that the world isn't in an unhealthy moral state.""Wouldn't think of it dearest. People lie, cheat, rape, swindle, kill, maim, torture and destroy. Bad thing. People also pop into bed together and cosy up. Good thing. If we think fucking is a sign of moral decay then we're a little bit stupid-stupid, aren't we?

Anger fed him and clothed him and he owed it much.

Look at the kind of people who most object to the childishness and cheapness of celebrity culture. Does one really want to side with such apoplectic and bombastic bores? I should know, I often catch myself being one, and it isn__ pretty. I will defend the absolute value of Mozart over Miley Cyrus, of course I will, but we should be wary of false dichotomies. You do not have to choose between one or the other. You can have both. The human cultural jungle should be as varied and plural as the Amazonian rainforest. We are all richer for biodiversity. We may decide that a puma is worth more to us than a caterpillar, but surely we can agree that the habitat is all the better for being able to sustain each. Monocultures are uninhabitably dull and end as deserts.

I will defend the absolute value of Mozart over Miley Cyrus, of course I will, but we should be wary of false dichotomies. You do not have to choose between one or the other. You can have both. The human cultural jungle should be as varied and plural as the Amazonian rainforest. We are all richer for biodiversity. We may decide that a puma is worth more to us than a caterpillar, but surely we can agree that the habitat is all the better for being able to sustain each.

We gave you a perfectly good language and you f***ed up.

There are all kinds of pedants around with more time to read and imitate Lynne Truss and John Humphrys than to write poems, love-letters, novels and stories it seems. They whip out their Sharpies and take away and add apostrophes from public signs, shake their heads at prepositions which end sentences and mutter at split infinitives and misspellings, but do they bubble and froth and slobber and cream with joy at language? Do they ever let the tripping of the tips of their tongues against the tops of their teeth transport them to giddy euphoric bliss? Do they ever yoke impossible words together for the sound-sex of it? Do they use language to seduce, charm, excite, please, affirm and tickle those they talk to? Do they? I doubt it. They__e too farting busy sneering at a greengrocer__ less than perfect use of the apostrophe. Well sod them to Hades. They think they__e guardians of language. They__e no more guardians of language than the Kennel Club is the guardian of dogkind.