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a typical chromosomal DNA molecule in a human being is composed of about five billion pairs of nucleotides_ But since there are four different kinds of nucleotides, the number of bits of information in DNA is four times the number of nucleotide pairs. Thus if a single chromosome has five billion (5 X 10^9) nucleotides, it contains twenty billion (2 X 10^10) bits of information_ We also see that if more than some tens of billions (several times 10^10) of bits of information are necessary for human survival, extragenetic systems will have to provide them: the rate of development of genetic systems is so slow that no source of such additional biological information can be sought in the DNA.
Carl Sagan Dragons of Eden: Speculations on the Evolution of Human Intelligence
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a typical chromosomal DNA molecule in a human being is composed of about five billion pairs of nucleotides_ But since there are four different kinds of nucleotides, the number of bits of information in DNA is four times the number of nucleotide pairs. Thus if a single chromosome has five billion (5 X 10^9) nucleotides, it contains twenty billion (2 X 10^10) bits of information_ We also see that if more than some tens of billions (several times 10^10) of bits of information are necessary for human survival, extragenetic systems will have to provide them: the rate of development of genetic systems is so slow that no source of such additional biological information can be sought in the DNA.
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Carl Sagan

Dragons of Eden: Speculations on the Evolution of Human Intelligence

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