significantly

I have every expectation that cancer will become known as the disease of human evolution trying and failing to adapt to a significantly changed environment.

There is a significant problem associated with burning large quantities of fossil fuels into the atmosphere. This pollution will change the electromagnetic transmission of the atmosphere and lead to an unnatural electromagnetic environment at the ground level where we all live. Once the electromagnetic environment has been significantly changed by these emissions, then we will be in a new era of evolution. It appears that we have already entered that era some time ago.